A structural biology perspective on NMDA receptor pharmacology and function
نویسندگان
چکیده
منابع مشابه
NMDA receptor subunits: function and pharmacology.
N-methyl-D-aspartate receptors (NMDARs) are glutamate-gated ion channels widely expressed in the central nervous system that play key roles in excitatory synaptic transmission. Because of their involvement in numerous neurological disorders, NMDARs are also targets of therapeutic interest. NMDARs occur as multiple subtypes which differ in their subunit composition and in their biophysical and p...
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ژورنال
عنوان ژورنال: Current Opinion in Structural Biology
سال: 2015
ISSN: 0959-440X
DOI: 10.1016/j.sbi.2015.07.012